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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK16 All Species: 28.18
Human Site: Y180 Identified Species: 51.67
UniProt: Q00536 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00536 NP_006192.1 496 55716 Y180 E G T Y A T V Y K G K S K L T
Chimpanzee Pan troglodytes XP_521035 762 83144 Y446 E G T Y A T V Y K G K S K L T
Rhesus Macaque Macaca mulatta XP_001100911 485 54881 D177 K G K S K L T D N L V A L K E
Dog Lupus familis XP_538015 500 56072 Y184 E G T Y A T V Y K G K S K L T
Cat Felis silvestris
Mouse Mus musculus Q04735 496 55895 Y180 E G T Y A T V Y K G K S K L T
Rat Rattus norvegicus Q63686 496 55746 Y180 E G T Y A T V Y K G K S K L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521338 549 61821 Y233 E G T Y A T V Y K G K S K L T
Chicken Gallus gallus XP_416161 516 58803 Y207 E G T Y A T V Y K G R S K L T
Frog Xenopus laevis Q6DJM7 435 49211 A157 L L K G L K H A N I V L L H D
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 H139 S L L K G L K H A N I V L L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48609 294 33162 T14 M E K I G E G T Y G T V F K G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P23111 294 33816 T14 V E K I G E G T Y G V V Y K A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 T14 V E K I G E G T Y G V V Y K A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58 89.3 97.5 N.A. 97.5 95.5 N.A. 76.1 69.1 45.1 41.9 N.A. 35.4 N.A. N.A. N.A.
Protein Similarity: 100 60.8 90.3 98 N.A. 98.9 97.3 N.A. 81 82.9 59.6 55.8 N.A. 43.9 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 100 93.3 0 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 100 0 13.3 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 33 N.A. 33.4 N.A. N.A.
Protein Similarity: N.A. 45.3 N.A. 46.3 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 54 0 0 8 8 0 0 8 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % D
% Glu: 54 24 0 0 0 24 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 62 0 8 31 0 24 0 0 77 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 24 0 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 8 0 39 8 8 8 8 0 54 0 47 0 54 31 0 % K
% Leu: 8 16 8 0 8 16 0 0 0 8 0 8 24 62 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 16 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 0 0 8 0 0 0 0 0 0 0 54 0 0 0 % S
% Thr: 0 0 54 0 0 54 8 24 0 0 8 0 0 0 54 % T
% Val: 16 0 0 0 0 0 54 0 0 0 31 31 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 54 0 0 0 54 24 0 0 0 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _